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Acetyl-l-Carnitine, Alpha Lipoic Acid, and CoQ10 Super Energy, Vitality, Anti-aging, and Antioxidant Formula
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5-HTP Acetyl-l-carnitine Alpha-GPC BioAssimilate Enzyme BioDiet Plus™ CHP Hangover Prevention CoQ10 100 mg CoQ10 60 mg with Omega-3 CoQ10 Ubiquinol DHEA GABA Glucosamine Chondroitin MSM Hyaluronic Acid with MSM L-theanine LIBIDOBLAST® Melatonin NEURO CLEAR™ Omega-3 Fish Oil Double Strength Omega-3 Fish Oil Enteric Coated Pregnenolone R-Alpha Lipoic Acid Resveratrol St. John's Wort |
The 3 main popular and effective ingredients in BioEndurance™ when combined work synergistically but are generally sold separately and are expensive. We have researched prices on these main ingredients when sold separately. Using the lowest prices we could find, here's the breakdown:
Acetyl-L-Carnitine 500 mg x 90 capsules = $41.38
Alpha Lipoic Acid 200 mg x 90 capsules = $28.78
CoQ10 20 mg x 90 capsules = $14.99
Total = $85.15
BioEndurance™ 90 capsule bottle - Sale Price only $43.60
About Ingredients:
Acetyl-l-carnitine is a molecule that occurs naturally in the brain, liver, and kidney. Natural levels of Acetyl-l-carnitine diminish as we age.
Common uses for supplemental Acetyl-l-carnitine:
Alzheimer's
The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function. Several double-blind clinical trials suggest that acetyl-L-carnitine delays the progression of Alzheimer’s disease and enhances overall performance in some people with Alzheimer’s disease. Alzheimer’s research has been done with the acetyl-L-carnitine form, rather than the L-carnitine form, of this nutrient.
Several clinical trials have found that acetyl-L-carnitine supplementation delays the progression of Alzheimer’s disease, improves memory, and enhances overall performance in some people with Alzheimer’s disease. Overall, most short-term studies have shown clinical benefits, and most long-term studies (one year) have shown a reduction in the rate of deterioration.
Brain
One double-blind trial has found that acetyl-L-carnitine may be helpful for people with degenerative cerebellar ataxia, a loss of muscular coordination caused by disease in the cerebellum (the hind part of the brain that controls muscle tone and balance).
Several clinical trials suggest that acetyl-L-carnitine delays onset of ARCD and improves overall cognitive function in the elderly. In a controlled clinical trial, acetyl-L-carnitine was given to elderly people with mild cognitive impairment. After 45 days of acetyl-L-carnitine supplementation at 1,500 mg per day, significant improvements in cognitive function (especially memory) were observed. Another large trial of acetyl-L-carnitine for mild cognitive impairment in the elderly found that 1,500 mg per day for 90 days significantly improved memory, mood, and responses to stress. The favorable effects persisted at least 30 days after treatment was discontinued. Controlled and uncontrolled clinical trials on acetyl-L-carnitine corroborate these findings.
Depression
Acetyl-L-carnitine may be effective for depression experienced by the elderly. A preliminary trial found that acetyl-L-carnitine supplementation was effective at relieving depression in a group of elderly people, particularly those showing more serious clinical symptoms. These results were confirmed in another similar clinical trial. In that trial, participants received either 500 mg three times a day of acetyl-L-carnitine or a matching placebo. Those receiving acetyl-L-carnitine experienced significantly reduced symptoms of depression compared to those receiving placebo. At least two other clinical studies of acetyl-L-carnitine for depression in the elderly have reported similar results.
Diabetes
Acetyl-L-carnitine prevents substance P loss in the sciatic nerve and lumbar spinal cord of diabetic animals.
Diabetic neuropathy is a disease of peripheral nerves, characterized by axonal atrophy and degeneration that might be preceded by a marked impairment of axonal transport and by a reduced conduction velocity. Sensory nerves are particularly susceptible to diabetes. In the present report it is shown that experimental diabetes in rats causes a significant reduction of the content of the pain-related neuropeptide substance P in sciatic nerve and lumbar spinal cord. Such a loss of substance P is fully prevented by acetyl-L-carnitine treatment. The neuroprotective pharmacological effect is selective and takes place without significant changes of hyperglycaemia and without modifications of the reduced rate of body growth typical of diabetic animals.
Di Giulio AM Gorio A Bertelli A Mantegazza P Ferraris L Ramacci MT
In: Int J Clin Pharmacol Res (1992) 12(5-6):243-6
Peptide alterations in autonomic diabetic neuropathy prevented by acetyl-L-carnitine.
Autonomic neuropathy and gastrointestinal problems are among the most common complications of diabetes. In this report it is shown that a possible correlation between the two disorders might exist, since diabetes causes a profound alteration of the peptidergic innervation of the gut. It is reported that 14 weeks after diabetes induction with alloxan the levels of substance P and methionine-enkephalin are markedly reduced throughout the intestine, while vasoactive intestinal polypeptide content is dramatically increased. Therefore the enteric innervation of diabetic animals is completely disorganized, with some systems undergoing atrophy and others undergoing hypertrophy. Treatment of diabetic animals with acetyl-L-carnitine prevents the onset of the marked peptide changes described above. The results suggest a potential for acetyl-L-carnitine in the treatment of autonomic neuropathies.
Gorio A Di Giulio AM Tenconi B Donadoni L Germani E Bertelli A Mantegazza P Maccari F Ramacci MT
In: Int J Clin Pharmacol Res (1992) 12(5-6):225-30
Drug interactions:
Are there any drug interactions? A. Didanosine (Depletion or interference) Didanosine is a drug that blocks reproduction of the human immunodeficiency virus (HIV). HIV is the virus that infects people causing acquired immunodeficiency syndrome (AIDS). Didanosine is used in combination with other drugs to treat HIV infection.
Acetyl-l-carnitine suggested dosage is 500 mg two to three times daily.
Alpha Lipoic Acid serves as a coenzyme in the energy production process in the cells which can provide quick bursts of energy. Alpha Lipoic Acid is unique in that it is both water and fat soluble witch allows it to enter all parts of the cell to neutralize free radicals. Alpha Lipoic Acid contributes to invigorating mental and physical energy and a reduction in muscle fatigue. Dr. Lester Packer, a leading researcher in the area of antioxidants and a professor of molecular and cell biology at the University of California at Berkeley says "Alpha-Lipoic acid could have far-reaching consequences in the search for prevention and therapy of chronic degenerative diseases such as diabetes and cardiovascular disease" .... "and because it’s the only antioxidant that can easily get into the brain, it could be useful in preventing damage from a stroke".
Common uses for supplemental alpha Lipoic Acid:
October 11, 2002. The incidence of inflammatory diseases such as arthritis increases with age. Free radicals promote inflammatory reactions, which antioxidants have been successful at diminishing. Scientists recently stimulated the inflammatory response of white blood cells, resulting in an increase of Intracellular Adhesion Molecule 1 (ICAM-1), which encourages white blood cells to stick to other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent antioxidant, was then added to the mix. Researchers said the acid reduced the activity of ICAM-1 to levels in normal, un-stimulated cells in a dose-dependent manner. It also lowered the activity of NFkB (NFkB can increase the activity of genes responsible for inflammation). According to the study, these changes suggest that alpha-lipoic acid may help reduce the effects of inflammatory diseases such a rheumatoid arthritis and psoriasis.
Suggested dosage for Alpha Lipoic Acid is 200 mg two to three times daily.
CoQ10 is a vitamin-like compound also called ubiquinone. It is an essential component of cells and is utilized by the mitochondria in the normal process of energy production. It helps convert food into energy at a very basic, cellular level and it is an antioxidant. CoQ10 (Coenzyme Q10) is one in a series of ubiquinones, naturally occurring compounds produced in nearly every cell of the body, and was discovered as recently as 1957. This Coenzyme Q10 is the highest quality available and synergistically blended with BioperineEwhich has been demonstrated to aid in absorption.
Doctors commonly prescribe CoQ10 (coenzyme Q10) to treat heart disease in Japan, Sweden, Italy, Canada, and other countries.
Common Uses for CoQ10:
Improves the heart and circulation in those with congestive heart failure, a weakened heart muscle (cardiomyopathy), high blood pressure, heart rhythm disorders, chest pain (angina), or Raynaud's disease.
Treats gum disease and maintains health gums and teeth.
Protects the nerves and may help slow Alzheimer's or Parkinson's disease.
May help prevent cancer and heart disease, and play a role in slowing down age-related degenerative changes.
May improve the course of AIDS or cancer. Q10 has shown small significant benefit in treating ALS, also known as Lou Gehrig's disease, and it has also has been used to treat a range of rare pediatric neurological diseases. Because any disease process that involves free radical damage could be treated with coenzyme Q10, the theoretical therapeutic potential of this compound seems limitless. Cataracts, macular degeneration, side effects of chemotherapy and skin damage related to radiation exposure could all be helped by doses of Q10, proponents believe. The primary function of CoQ10 (coenzyme Q10) is as a catalyst for metabolism - the complex chain of chemical reactions during which food is broken down into packets of energy that the body can use. Acting in conjunction with enzymes, the compound speeds up the vital metabolic process, providing the energy that the cells need to digest food, heal wounds, maintain healthy muscles, and perform countless other bodily functions. Because of the nutrient's essential role in energy production, it's not surprising that it is found in every cell in the body. It is especially abundant in the energy-intensive cells of the heart, helping this organ beat more than 100,000 times each day. In addition, coenzyme Q10 acts as an antioxidant, much like vitamins C and E, helping to neutralize the cell-damaging molecules known as free radicals.
CoQ10 (Coenzyme Q10) may play a role in preventing cancer, heart attacks, and other diseases linked to free-radical damage. It's also used as a general energy enhancer and anti-aging supplement. Because levels of the compound diminish with age (and with certain diseases), some doctors recommend daily supplementation beginning about age 40. CoQ10 has generated much excitement as a possible therapy for heart disease, especially congestive heart failure or a weakened heart. In some studies, patients with a poorly functioning heart have been found to improve greatly after adding the supplement to their conventional drugs and therapies. Other studies have shown that people with cardiovascular disease have low levels of this substance in their heart. Further research suggest that CoQ10 may protect against blood clots, lower high blood pressure, diminish irregular heartbeats, treat mitral valve prolapse, lessen symptoms of Raynaud's disease (poor circulation in the extremities), and relieve chest pains (angina). A few small studies suggest that CoQ10 may prolong survival in those with breast or prostate cancer, though results remain inconclusive. It also appears to aid healing and reduce pain and bleeding in those with gum disease, and speed recovery following oral surgery. CoQ10 shows some promise against Parkinson's and Alzheimer's Diseases and fibromyalgia, and it may improve stamina in those with AIDS. Certain practitioners believe the nutrient helps stabilize blood sugar levels in people with diabetes. There are many other claims make for CoQ10 that it slows aging, aids weight loss, enhances athletic performance, combats chronic fatigue syndrome, relieves multiple allergies, and boosts immunity. For daily supplementation, the dosage range is from 30 - 100 mg, with the most common dosage at 30 mg. It takes up to eight weeks to see results with CoQ10. There are no known significant side effects or drug interactions.
The above statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 90
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ONE CAPSULE PROVIDES: Acetyl-l-carnitine HCI 500 mg Alpha Lipoic Acid 200 mg Coenzyme Q10 20 mg Bioperine (black pepper extract) 5 mg |
% Daily Value * * * * |
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